학력

1991. 02. 전남대학교 의과대학 졸업(의학사)

2000. 02. 전남대학교 대학원 의학과(박사)

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경력

1996. 전남대학교 의과대학 신경과학교실 전공의 수료 및 전문의 취득

1999. 전남대학교병원 신경과 전임의사

2000. 전남대학교병원 신경과 임상교수요원

2004. 전남대학교 의과대학 신경과학교실 조교수

2008. 전남대학교 의과대학 신경과학교실 부교수

2006. - 2008. 미국 New York대학병원 알츠하이머병센터 연수

2009. 대한중환자의학회 세부전문의 수료

2012. 영국 Bristol대학 MRC for synaptic plasticity 센터 연수

2017. - 2020. 전남대학교병원 의생명연구원장

현재 전남대학교 의과대학 신경과학교실 교수

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경력 중 수상경력

2009. 대한치매학회지 우수증례상

2016. 대한치매학회지 우수논문상

2019. 보건복지부장관상

2019. 전남대학교총장상

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기타활동

전남의대학술지 편집위원

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연구업적

2020. Choi SM, Cho SH, Kim BC. Association between freezing of gait and bone mineral density in patients with Parkinson's disease. Neurol Sci. 2020 Nov 23. doi: 10.1007/s10072-020-04920-6. Epub ahead of print. PMID: 33230756.

2020. Kim YJ, Kim SH, Park Y, Park J, Lee JH, Kim BC, Song WK. miR-16-5p is upregulated by amyloid β deposition in Alzheimer's disease models and induces neuronal cell apoptosis through direct targeting and suppression of BCL-2. Exp Gerontol. 2020 Jul 15;136:110954. doi: 10.1016/j.exger.2020.110954. Epub 2020 Apr 19. PMID: 32320719.

2020. Lim HJ, Park JE, Kim BC, Choi SM, Song MK, Cho SH, Seo HJ, Kim J, Song HC, Choi KY, Lee JJ, Kim HW, Ha JM, Song WK, Park SG, Lee JS, Lee KH. Comparison of Two Analytical Platforms in Cerebrospinal Fluid Biomarkers for the Classification of Alzheimer's Disease Spectrum with Amyloid PET Imaging. J Alzheimers Dis. 2020;75(3):949-958. doi: 10.3233/JAD-191331. PMID: 32390627.

2020. Choi YY, Lee JJ, Choi KY, Seo EH, Choo IH, Kim H, Song MK, Choi SM, Cho SH, Kim BC, Lee KH. Corrigendum: The Aging Slopes of Brain Structures Vary by Ethnicity and Sex: Evidence From a Large Magnetic Resonance Imaging Dataset From a Single Scanner of Cognitively Healthy Elderly People in Korea. Front Aging Neurosci. 2020 Nov 9;12:604238. doi: 10.3389/fnagi.2020.604238. Erratum for: Front Aging Neurosci. 2020 Aug 12;12:233. PMID: 33240082; PMCID: PMC7680844.

2020. Seo HJ, Park JE, Choi SM, Kim T, Cho SH, Lee KH, Song WK, Song J, Jeong HS, Kim DH, Kim BC. Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's Disease. Int J Mol Sci. 2021 Jan 12;22(2):698. doi: 10.3390/ijms22020698. PMID: 33445678; PMCID: PMC7828160.

2019. Han HJ, Kim BC, Youn YC, Jeong JH, Kim JH, Lee JH, Park KH, Park KW, Kim EJ, Oh MS, Shim YS, Park HY, Yoon B, Yoon SJ, Cho SJ, Park KC, Na DL, Park SA, Lee JM, Choi SH. A Comparison Study of Cilostazol and Aspirin on Changes in Volume of Cerebral Small Vessel Disease White Matter Changes: Protocol of a Multicenter, Randomized Controlled Trial. Dement Neurocogn Disord. 2019 Dec;18(4):138-148. doi: 10.12779/dnd.2019.18.4.138. Epub 2019 Dec 13. PMID: 31942173; PMCID: PMC6946612.

2019. Kim D, Kim HS, Choi SM, Kim BC, Lee MC, Lee KH, Lee JH. Primary Age-Related Tauopathy: An Elderly Brain Pathology Frequently Encountered during Autopsy. J Pathol Transl Med. 2019 May;53(3):159-163. doi: 10.4132/jptm.2019.03.14. Epub 2019 Mar 19. PMID: 30887795; PMCID: PMC6527938.

2019. Kang MJ, Kim SY, Na DL, Kim BC, Yang DW, Kim EJ, Na HR, Han HJ, Lee JH, Kim JH, Park KH, Park KW, Han SH, Kim SY, Yoon SJ, Yoon B, Seo SW, Moon SY, Yang Y, Shim YS, Baek MJ, Jeong JH, Choi SH, Youn YC. Prediction of cognitive impairment via deep learning trained with multi-center neuropsychological test data. BMC Med Inform Decis Mak. 2019 Nov 21;19(1):231. doi: 10.1186/s12911-019-0974-x. PMID: 31752864; PMCID: PMC6873409.

2019. Gupta Y, Lee KH, Choi KY, Lee JJ, Kim BC, Kwon GR; National Research Center for Dementia; Alzheimer’s Disease Neuroimaging Initiative. Early diagnosis of Alzheimer's disease using combined features from voxel-based morphometry and cortical, subcortical, and hippocampus regions of MRI T1 brain images. PLoS One. 2019 Oct 4;14(10):e0222446. doi: 10.1371/journal.pone.0222446. PMID: 31584953; PMCID: PMC6777799.

2019. Ryu T, Park HJ, Kim H, Cho YC, Kim BC, Jo J, Seo YW, Choi WS, Kim K. Improved memory and reduced anxiety in δ-catenin transgenic mice. Exp Neurol. 2019 Aug;318:22-31. doi: 10.1016/j.expneurol.2019.04.006. Epub 2019 Apr 11. PMID: 30981806.

2019. Choi KY, Lee JJ, Gunasekaran TI, Kang S, Lee W, Jeong J, Lim HJ, Zhang X, Zhu C, Won SY, Choi YY, Seo EH, Lee SC, Gim J, Chung JY, Chong A, Byun MS, Seo S, Ko PW, Han JW, McLean C, Farrell J, Lunetta KL, Miyashita A, Hara N, Won S, Choi SM, Ha JM, Jeong JH, Kuwano R, Song MK, An SSA, Lee YM, Park KW, Lee HW, Choi SH, Rhee S, Song WK, Lee JS, Mayeux R, Haines JL, Pericak-Vance MA, Choo ILH, Nho K, Kim KW, Lee DY, Kim S, Kim BC, Kim H, Jun GR, Schellenberg GD, Ikeuchi T, Farrer LA, Lee KH, Neuroimaging Initative AD. APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample. J Clin Med. 2019 Aug 16;8(8):1236. doi: 10.3390/jcm8081236. PMID: 31426376; PMCID: PMC6723529.

2019. Sim KY, Park SH, Choi KY, Park JE, Lee JS, Kim BC, Gwak J, Song WK, Lee KH, Park SG. High-throughput epitope profiling of antibodies in the plasma of Alzheimer's disease patients using random peptide microarrays. Sci Rep. 2019 Mar 14;9(1):4587. doi: 10.1038/s41598-019-40976-x. PMID: 30872784; PMCID: PMC6418098.

2019. Gupta Y, Lee KH, Choi KY, Lee JJ, Kim BC, Kwon GR. Alzheimer's Disease Diagnosis Based on Cortical and Subcortical Features. J Healthc Eng. 2019 Mar 3;2019:2492719. doi: 10.1155/2019/2492719. PMID: 30944718; PMCID: PMC6421724.

2019. Park JE, Choi KY, Kim BC, Choi SM, Song MK, Lee JJ, Kim J, Song HC, Kim HW, Ha JM, Seo EH, Song WK, Park SG, Lee JS, Lee KH. Cerebrospinal Fluid Biomarkers for the Diagnosis of Prodromal Alzheimer's Disease in Amnestic Mild Cognitive Impairment. Dement Geriatr Cogn Dis Extra. 2019 Mar 12;9(1):100-113. doi: 10.1159/000496920. PMID: 31011328; PMCID: PMC6465729.

2019. Choi SM, Yoon GJ, Jung HJ, Kim BC. Analysis of characteristics affecting instrumental activities of daily living in Parkinson's disease patients without dementia. Neurol Sci. 2019 Jul;40(7):1403-1408. doi: 10.1007/s10072-019-03860-0. Epub 2019 Apr 1. PMID: 30931509.

2019. Choi SM, Jung HJ, Yoon GJ, Kim BC. Factors associated with freezing of gait in patients with Parkinson's disease. Neurol Sci. 2019 Feb;40(2):293-298. doi: 10.1007/s10072-018-3625-6. Epub 2018 Nov 1. PMID: 30386934.

2018. Choi GS, Kim GH, Choi JH, Hwang J, Kwon E, Lee SA, Kong KA, Kang HJ, Yoon B, Kim BC, Yang DW, Na DL, Kim EJ, Na HR, Han HJ, Lee JH, Kim JH, Lee KY, Park KH, Park KW, Kim S, Han SH, Kim SY, Yoon SJ, Moon SY, Youn YC, Choi SH, Jeong JH. Age-Specific Cutoff Scores on a T1-Weighted Axial Medial Temporal-Lobe Atrophy Visual Rating Scale in Alzheimer's Disease Using Clinical Research Center for Dementia of South Korea Data. J Clin Neurol. 2018 Jul;14(3):275-282. doi: 10.3988/jcn.2018.14.3.275. PMID: 29971973; PMCID: PMC6031994

2018. Park KW, Hong YJ, Park JH, Park H, Cheon SM, Kim JW, Kim BC, Jeong YJ, Yoon HJ, Kang DY. Pattern of cerebral hypoperfusion according to the clinical staging in dementia with Lewy bodies. Neurocase. 2018 Apr;24(2):83-89. doi: 10.1080/13554794.2018.1447133. Epub 2018 Mar 6. PMID: 29508646.

2018. Choi SM, Kim BC, Cho BH, Kang KW, Choi KH, Kim JT, Lee SH, Park MS, Kim MK, Cho KH. Comparison of two motor subtype classifications in de novo Parkinson's disease. Parkinsonism Relat Disord. 2018 Sep;54:74-78. doi: 10.1016/j.parkreldis.2018.04.021. Epub 2018 Apr 18. PMID: 29703644.

2016. Choi YJ, Kang KW, Lee SY, Kang SH, Lee SH, Kim BC. Creutzfeldt-Jakob Disease Presenting With Dizziness and Gaze-Evoked Nystagmus: A Case Report. Medicine (Baltimore). 2016 Feb;95(7):e2766. doi: 10.1097/MD.0000000000002766. PMID:26886621

2015. Yi JH, Park HJ, Lee S, Jung JW, Kim BC, Lee YC, Ryu JH, Kim DH. Cassia obtusifolia seed ameliorates amyloid β-induced synaptic dysfunction through anti-inflammatory and Akt/GSK-3β pathways. J Ethnopharmacol. 2016 Feb 3;178:50-7. doi: 10.1016/j.jep.2015.12.007. Epub 2015 Dec 7. PMID:26674159

2015. Yi JH, Park HJ, Kim BC, Kim DH, Ryu JH. Evidences of the role of the rodent hippocampus in the non-spatial recognition memory. Behav Brain Res. 2016 Jan 15;297:141-9. doi: 10.1016/j.bbr.2015.10.018. Epub 2015 Oct 20. PMID:26467606

2015. Hyun Yi J, Hye Jin Park, Ji Beak S, Lee S, Wook Jung J, Kim BC, Hoon Ryu J, Hyun Kim D. Danggui-Jakyak-San enhances hippocampal long-term potentiation through the ERK/CREB/BDNF cascade. J Ethnopharmacol. 2015 Dec 4;175:481-9. doi: 10.1016/j.jep.2015.10.012. Epub 2015 Oct 8.PMID:26453932

2015. Kim JT, Heo SH, Choi KH, Nam TS, Choi SM, Lee SH, Park MS, Kim BC, Kim MK, Saver JL, Cho KH. Clinical Implications of Changes in Individual Platelet Reactivity to Aspirin Over Time in Acute Ischemic Stroke. Stroke. 2015 Sep;46(9):2534-40. doi: 10.1161/STROKEAHA.115.009428. Epub 2015 Jul 28.PMID:26219647

2015. Yoon W, Kim SK, Park MS, Kim BC, Kang HK. Endovascular treatment and the outcomes of atherosclerotic intracranial stenosis in patients with hyperacute stroke. Neurosurgery. 2015 Jun;76(6):680-6. doi: 10.1227/NEU.0000000000000694. PMID:25988927

2015. Choi SM, Kim BC, Chang J, Choi KH, Nam TS, Kim JT, Lee SH, Park MS, Yoon W, de Leon MJ. Comparison of the Brain Volume in Essential Tremor and Parkinson's Disease Tremor Using an Automated Segmentation Method. Eur Neurol. 2015 Apr 29;73(5-6):303-309.

2015. Kim JT, Heo SH, Lee JS, Choi MJ, Choi KH, Nam TS, Lee SH, Park MS, Kim BC, Kim MK, Cho KH. Aspirin resistance in the acute stages of acute ischemic stroke is associated with the development of new ischemic lesions. PLoS One. 2015 Apr 7;10(4):e0120743.

2015. Choi KH, Park MS, Kim HS, Kim KT, Kim HS, Kim JT, Kim BC, Kim MK, Park JT, Cho KH. Alpha-lipoic acid treatment is neurorestorative and promotes functional recovery after stroke in rats. Mol Brain. 2015 Feb 11;8(1):9.

2015. Choi YJ, Lee SH, Park MS, Kim BC, Kim MK. Midbrain infarction presenting with monocular elevation palsy and ptosis: topographic lesion analysis. J Neuroophthalmol. 2015 Jun;35(2):175-8.

2015. Park HK, Choi SH, Park SA, Kim HJ, Lee Y, Han SH, Kim EJ, Kim BC, Han HJ, Moon SY, Yang DW, Park KW, Park KH, Yoon B, Seo SW, Na DL, Na HR, Lee JH. Cognitive profiles and neuropsychiatric symptoms in Korean early-onset Alzheimer's disease patients: a CREDOS study. J Alzheimers Dis. 2015;44(2):661-73

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저서

치매 임상적접근 3판

임상신경과학

신경학3판

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특허

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학회활동

대한신경과학회 정회원

대한치매학회 정회원 및 무임소이사

대한노인신경의학회 정회원 및 무임소이사

대한 파킨슨병 및 이상운동질환학회 정회원

대한뇌졸중학회 정회원

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